Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of S1PR5 in mouse tissue homogenates, cell lysates.
Target Information: The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1\, MIM 601974) are S1P receptors\, others (e.g., EDG2\, MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]